Molecular biology of B-cell and T-cell development

"In Molecular Biology of B-Cell and T-Cell Development, leading experimentalists critically review current research on the molecular mechanisms determining the early development of B and T lymphocytes and other hematopoietic cell types. These cutting-edge reviews explore the molecular microenvironment in hematopoiesis and lymphoid development, demonstrate which ligands and receptors are most critical in these cell - cell interactions, as well as which are the triggering receptors, signaling pathways, and developmental checkpoints controlling correct development of B- and T-cells. The vital roles played by transcription factor combinations in establishing cell identity are compared in the erythroid, myeloid, B, and T lineages."--BOOK JACKET.