Status epilepticus

Status epilepticus, the maximum expression of epilepsy, is a distinctive condition, much more than simply a severe version of ordinary epilepsy. This is the definitive reference work on the subject, taking a modern look at the clinical features, pathophysiology and treatment of status, in both children and adults. All forms of status are considered, including the classical convulsive (grand mal) type, the less well-understood yet common and fascinating nonconvulsive variants, boundary syndromes and also pseudostatus epilepticus. The history, clinical aspects, treatment and outcome of each form are explored in their scientific context, accounting for research findings in the fields of epidemiology, neurophysiology, neuroanatomy, neuropathology, neurochemistry and neuropharmacology. Received ideas are examined critically, the existing schemes of classification revised, and current practice is challenged where it seems inadequate. Treatment is dealt with in depth, and schemes of management outlined for both convulsive and nonconvulsive forms. For each drug used in status, a systematic review is given of the pharmacology, clinical and toxic effects in status, administration and dosage.