irritation

noun

1. the psychological state of being irritated or annoyed
2. a sudden outburst of anger"his temper sparked like damp firewood"
3. (pathology) abnormal sensitivity to stimulation"any food produced irritation of the stomach"
4. the neural or electrical arousal of an organ or muscle or gland
5. an uncomfortable feeling of mental painfulness or distress
6. unfriendly behavior that causes anger or resentment
7. the act of troubling or annoying someone